How do you read wheal flare allergy test results?
How do you read wheal flare allergy test results?
After the allergen extracts are placed on the skin, your physician looks for signs of an allergic response. A positive response appears in the form of a raised bump or wheal, surrounded by a red area, or flare. The size of the wheal and flare shows roughly how much allergic IgE antibody you have made to that allergen.
What does class 5 allergy mean?
Class 5: Very high level of allergy (50.00 KUA/L – 99.9 KUA/L) indicative of very high level sensitization. Class 6: Very high level of allergy (≥ 100.0 KUA/L) indicative of very high level sensitization.
What is considered a high IgE level?
Table. IgE level test ratings and interpretations
| Rating of specific IgE level (kUA/L) | Grade/Class | Interpretation |
|---|---|---|
| Low (0.35–0.69) | I | Doubtful significance |
| Moderate (0.70–3.49) | II | Possible |
| High (3.50–17.49) | III | More possible |
| Very high (17.50–49.99) | IV | More likely |
What is IgE normal range?
Variations in the upper limit of normal total serum IgE have been reported: they can range from 150 to 1,000 UI/ml; but the usually accepted upper limit is between 150 and 300 UI/ml.
What does 3 allergy test mean?
A test is positive if the allergen causes a wheal 3 mm greater than the negative control, and if the skin has a response to the histamine, as well. It is important to know that individuals cannot undergo skin testing if they are using antihistamines, since this blocks the histamine-mediated reaction.
Can you feel sick after allergy testing?
Skin testing is generally well tolerated. The most common reaction is local itching and swelling of the test site which resolves within a few hours. Other possible side-effects include itching of the eyes, nose, throat; runny nose, wheezing, light-headedness, hives and nausea.
What does IgE class mean?
Classes provide an indication of the severity of a suspected allergen. Each result will fall in a class, and each of the classes will fall within a reactivity level. Intensity ranges are the cut-offs that define the classes. These are specific to the instrument measuring your IgE concentration in the lab.
What causes very high IgE levels?
Diseases which cause the elevation of serum IgE levels include atopic diseases (asthma, allergic rhinitis, atopic dermatitis, urticaria), parasitic diseases, cutaneous diseases, neoplastic diseases, and immune deficiencies [3].
What does IgE level indicate?
Allergy blood tests measure the amount of IgE antibodies in the blood. A small amount of IgE antibodies is normal. A larger amount of IgE may mean you have an allergy.
What is IgE level for asthma?
Results: Mean IgE levels ranged from 151.95 IU/ml in normal subjects to 1045.32 IU/ml in severe asthmatics. The model developed was 27% efficient.