Popular articles

What is toremifene used for?

What is toremifene used for?

Descriptions. Toremifene is used to treat metastatic breast cancer (cancer that has spread) that is hormone-receptor positive in women who have already stopped menstruating (postmenopausal).

What is the difference between tamoxifen and toremifene?

Methods: Toremifene is structurally similar to tamoxifen, differing only by a single chlorine atom, and has a similar pharmacologic profile. The major difference between the two compounds is in the preclinical activity; chronic, high-dose tamoxifen is hepatocarcinogenic in the rat, whereas toremifene is not.

Is toremifene a type of chemotherapy?

Fareston (toremifene citrate) is an estrogen agonist/antagonist that blocks estrogen from reaching cancer cells used to slow the growth of metastatic breast cancer (cancer that has spread from the original tumor). Unlike chemotherapy, Fareston does not actually destroy cancer cells.

Does toremifene increase testosterone?

Toremifene administration resulted in a significant increase in FSH, testosterone, SHBG, and inhibin B levels, as well as in sperm concentration, percentage motility and normal sperm forms.

Does toremifene affect blood pressure?

Toremifene can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Does tamoxifen increase LH and FSH?

The administration of tamoxifen, 20 mg/day for 10 days, to normal males produced a moderate increase in luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, and estradiol levels, comparable to the effect of 150 mg of clomiphene citrate (Clomid).

Does Fareston cause weight gain?

Other side effects: Headache, swelling of the hands and/or feet, dizziness, weight gain, vaginal discharge, and insomnia. Mood changes or depression can occur. Please talk to your healthcare provider if you feel that you are troubled by these side effects.

Does Nolvadex increase testosterone?

When used in combination with other PCT supplements such as Nolvadex, it can help restore normal testosterone production and minimize the risk of side effects in just 4 weeks.

Does fulvestrant come in pill form?

Drug forms and administration You’ll receive Faslodex injections at your doctor’s office. You’ll get Faslodex injections on days 1, 15, and 29 of your treatment. After the first three doses, you’ll get Faslodex injections once a month. Arimidex comes as an oral tablet that’s taken once a day.

What are the uses of toremifene?

Toremifene is used in postmenopausal women to treat metastatic breast cancer (cancer that has spread to other parts of the body). Toremifene may also be used for purposes not listed in this medication guide.

Does toremifene cause liver damage?

Toremifene is a nonsteroidal antiestrogen that is used in the treatment of estrogen receptor positive breast cancer. Long term toremifene therapy has been associated with development of fatty liver, steatohepatitis, cirrhosis, and rare instances of clinically apparent acute liver injury.

Where can I find FDA label information for toremifene?

FDA label information for this drug is available at DailyMed. Toremifene is approved to treat: Breast cancer that has metastasized (spread to other parts of the body). It is used in postmenopausal women whose cancer is estrogen receptor positive (ER+) or when it is not known if the cancer is ER+ or estrogen receptor negative (ER-).

What is the difference between toremifene and toremifene citrate?

Toremifene is the generic name of the drug and its INN and BAN, while toremifene citrate is its USAN and JAN and torémifène is its DCF. Toremifene is marketed almost exclusively under the brand name Fareston.