What does the drug vinblastine do?

Vinblastine is in a class of medications called vinca alkaloids. It works by slowing or stopping the growth of cancer cells in your body.

How is mitomycin C administered?

Mitomycin is given directly into the bladder (called intravesicular), through a catheter, and left in the bladder for 1-2 hours. The dosage and schedule is determined by your healthcare provider. This drug is blue in color and may make your urine blue-green in color. This can last up to two days after each dose.

What happens if you touch mitomycin?

* Contact can irritate the skin and eyes. * High exposure may cause poor appetite, fever, nausea, headache, fatigue and drowsiness. * Repeated contact can cause severe eye damage. * Repeated high exposure may affect the liver, kidneys and blood cells.

What is mitomycin made from?

Mitomycin is an antitumor antibiotic that is made from a soil fungus called Streptomyces caespitosus. Mitomycin inhibits DNA synthesis by producing DNA cross-links which halt cell replication and eventually cause cell death.

Do you lose your hair with mitomycin?

Mitomycin sometimes causes a temporary loss of hair. After treatment has ended, normal hair growth should return. After you stop using this medicine, it may still produce some side effects that need attention.

How does vinblastine prevent tumor growth?

Vinblastine works by stopping the cancer cells from separating into 2 new cells. So it blocks the growth of the cancer.

Is reserpine a tranquilizer?

Reserpine is used as a long-acting tranquilizer to subdue excitable or difficult horses and has been used illicitly for the sedation of show horses, for-sale horses, and in other circumstances where a “quieter” horse might be desired.

What is the difference between mitomycin and mitomycin C?

Mitomycin-C and MTC are other names for Mitomycin. In some cases, health care professionals may use the trade name Mutamycin or other names Mitomycin-C and MTC when referring to the generic drug name Mitomycin. Drug type: Mitomycin-C is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.

What type of chemo is mitomycin?

Drug type: Mitomycin is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “antitumor antibiotic.” (For more detail, see “How this drug works” section below).

What is mitomycin?

Mitomycin is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Is mitomycin C a cytotoxic?

Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein synthesis at high concentrations. (NCI04) Mitomycin is a cytotoxic antibiotic which is used as anticancer therapy of advanced cancers of the stomach and pancreas.

What is the half life of mitomycin in humans?

/Mitomycin/ has an alpha half-life of 5-10 min after IV injection and beta half-life of 46 min. Mitomycin is activated in vivo to a bifunctional and trifunctional alkylating agent. Binding to DNA leads to cross-linking and inhibition of DNA synthesis and function.

How does bioreduced mitomycin C work?

Bioreduced mitomycin C generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-links, thereby inhibiting DNA synthesis. Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein synthesis at high concentrations. (NCI04) Mitomycin c appears as blue-violet crystals. Used as an anti-tumor antibiotic complex.

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