What is Dysgerminoma ovary?
What is Dysgerminoma ovary?
(DIS-jer-mih-NOH-muh) A type of cancer that begins in germ cells in females. Germ cells are cells that form sperm in males or eggs in females. Dysgerminomas occur most often in the ovaries, but they may also occur in other areas of the body, including the central nervous system.
What does Dysgerminoma produce?
Dysgerminoma is the most common malignant ovarian germ cell tumor of children and adolescents, and makes up one third of malignant ovarian GCTs.
Which neoplasm is associated with gonadal dysgenesis?
This review describes the germ cell neoplasms that are malignant and most commonly associated with several types of gonadal dysgenesis. The most common neoplasm is gonadoblastoma, while others including dysgerminomas, yolk-sac tumors and teratomas are rare but can occur.
How is dysgerminoma diagnosed?
The diagnosis of dysgerminomas requires either laparoscopy or laparotomy….The standard workup for suspected dysgerminomas includes the following tumor markers:
- Lactate dehydrogenase (LDH)
- Beta-human chorionic gonadotropin (beta-hCG)
- Alpha-fetoprotein (AFP)
- Inhibin A and B.
- Cancer antigen 125 – For epithelial tumors.
What is the tumor marker for dysgerminoma?
The standard workup for suspected dysgerminomas includes the following tumor markers: Lactate dehydrogenase (LDH) Beta-human chorionic gonadotropin (beta-hCG) Alpha-fetoprotein (AFP)
Which of the following is example of gonadal dysgenesis?
Clinical manifestation include primary amenorrhea, hypergonadotropic hypogonadism, streak gonads, infertility, and failure to develop secondary sex characteristics.
Is gonadal dysgenesis inherited?
46, XX complete gonadal dysgenesis is inherited in an autosomal recessive pattern, and several loci and genes have been implicated; however, the exact intricacies of what causes this type of gonadal dysgenesis is unclear.