What are FKRP related disorders?

FKRP-related disorders are part of a family of muscle disorders caused by changes to a particular protein called alpha-dystroglycan.

What is Fukuyama congenital muscular dystrophy?

Fukuyama congenital muscular dystrophy is an inherited condition that predominantly affects the muscles , brain , and eyes . Congenital muscular dystrophies are a group of genetic conditions that cause muscle weakness and wasting (atrophy) beginning very early in life.

What are the symptoms of limb-girdle muscular dystrophy?

Signs and Symptoms of Limb-Girdle Muscular Dystrophy

• Toe walking, or walking on the balls of the feet.
• Walking with a waddling gait.
• Inability to rise from a squatting position without using the arms for leverage.
• Difficulty running.
• Abnormal curvature of the spine, such as lordosis and scoliosis.
• Joint stiffness.

How is congenital muscular dystrophy treated?

Specific treatment options may include physical and occupational therapy to improve muscle strength and prevent contractures; speech therapy; the use of various devices (e.g., canes, braces, walkers, wheelchairs) to assist with walking (ambulation) and mobility; surgery to correct skeletal abnormalities such as …

How long can you live with limb-girdle muscular dystrophy?

In its most common form, Limb-girdle muscular dystrophy causes progressive weakness that begins in the hips and moves to the shoulders, arms, and legs. Within 20 years, walking becomes difficult or impossible. Sufferers typically live to middle age to late adulthood.

Does LGMD affect the brain?

The brain, the intellect, and the senses are usually unaffected in LGMD.

Is Becker muscular dystrophy curable?

Becker Muscular Dystrophy Treatment There is not a cure for Becker muscular dystrophy at present. A doctor may prescribe steroid medications to help individuals remain able to walk for as long as possible. The clinical course of Becker muscular dystrophy is variable.