Which complex is used as anticancer drug?
Which complex is used as anticancer drug?
A platinum complex [PtCl2(NH3)2] known as cis− platin is used as an anticancer agent.
What complexes show anticancer property?
Platinum and Palladium Polyamine Complexes as Anticancer Agents: The Structural Factor.
Which anticancer drug belongs to inorganic metal complexes?
Answer and Explanation: The anticancer drug belonging to inorganic metal complexes is cisplatin. Cisplatin is the medicine which generally used in chemotherapy for curing…
Is platinum is an anticancer drug it is an example for?
Cisplatin, carboplatin and oxaliplatin are platinum-based drugs that are widely used in cancer chemotherapy. Platinum–DNA adducts, which are formed following uptake of the drug into the nucleus of cells, activate several cellular processes that mediate the cytotoxicity of these platinum drugs.
Which metal is used in chemotherapy?
Platinum drugs, such as cisplatin, carboplatin and oxaliplatin, are the mainstay of the metal-based compounds in the treatment of cancer, but the delay in the therapeutic accomplishment of other metal-based compounds hampered the progress of research in this field.
Why cisplatin is used as an anticancer drug?
Abstract. Cisplatin is one of the most effective anticancer agents widely used in the treatment of solid tumors. It is generally considered as a cytotoxic drug which kills cancer cells by damaging DNA and inhibiting DNA synthesis.
What medications contain platinum?
Platinum-based anticancer drugs, including cisplatin, carboplatin, oxaliplatin, nedaplatin, and lobaplatin, are heavily applied in chemotherapy regimens.
Why is platinum used in chemotherapy?
So, why platinum? Well, drugs like cisplatin are platinum compounds – which means they are made up of platinum and other elements. Platinum compounds like these all work by causing damage to the DNA of cancer cells to prevent them from multiplying.
When is cisplatin used?
Cisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar platinum-based drugs were developed with National Cancer Institute (NCI) support.
Does cisplatin contain platinum?
Cisplatin, a platinum-based drug, is used in combination chemotherapy for a wide range of solid tumors.
Is cisplatin a metal?
Which one of these antineoplastic anticancer drugs contains platinum?
Can non-platinum metal complexes be used as anti-cancer drugs?
Non platinum metal complexes as anti-cancer drugs The development of metal complexes with platinum central atoms such as cisplatin or carboplatin had an enormous impact on current cancer chemotherapy.
Is there a role for platinum in cancer treatment?
The development of metal complexes with platinum central atoms such as cisplatin or carboplatin had an enormous impact on current cancer chemotherapy. However, the spectrum of cancers that can be treated with platinum agents is narrow and treatment efficacy suffers from side effects and resistance p …
What are the metal-based anticancer drugs?
This forms the foundation for the modern era of the metal-based anticancer drugs. Platinum drugs, such as cisplatin, carboplatin and oxaliplatin, are the mainstay of the metal-based compounds in the treatment of cancer, but the delay in the therapeutic accomplishment of other metal-based compounds hampered the progress of research in this field.
Do metal-based complexes have ambivalent properties in cancer treatment?
Conclusion Since the discovery of cisplatin, a great deal of research has been conducted in the therapeutic application of metal-based complexes. These compounds exhibit ambivalent dispositions: some are associated with induction and progression of cancers, some have demonstrated efficacy in cancer treatment and some display both properties.