Why is antineoplastic hazardous?

Why is antineoplastic hazardous?

Hazardous drugs include antineoplastic agents which are used to treat cancer. Many of these antineoplastics bind to or damage DNA (for example alkylating agents), interfere with cell growth and proliferation, or interfere with DNA synthesis.

What are the side effects of antineoplastic drugs?

Side effects can include:

  • bone marrow suppression.
  • bruising easily.
  • anemia.
  • hair loss.
  • nausea and vomiting.
  • loss of appetite.
  • diarrhea and constipation.
  • changes in mood.

What are antineoplastic activities?

Antineoplastic: Acting to prevent, inhibit or halt the development of a neoplasm (a tumor). An agent with antineoplastic properties. For example, oxaliplatin (Eloxatin) is an antineoplastic used in the treatment of metastatic colon cancer.

Is antineoplastic the same as chemotherapy?

Antineoplastic drugs are medications used to treat cancer. Antineoplastic drugs are also called anticancer, chemotherapy, chemo, cytotoxic, or hazardous drugs. These drugs come in many forms.

How do you handle an antineoplastic agent?

Avoid skin contact with liquid antineoplastic drugs by always wearing two pairs of chemotherapy gloves and a nonabsorbent gown with a closed front and tight fitting cuffs during administration activities.

What is the most common and potentially serious complication of antineoplastic medication?

Many of the medications used to manage the most common toxicities of antineoplastic therapies further alter body functions and can perpetuate a decline in functioning. One of the most common side effects of many antineoplastic drugs therapies is nausea/vomiting (N/V).

Is an antineoplastic a chemo drug?

What happens if you touch Mitomycin?

* Contact can irritate the skin and eyes. * High exposure may cause poor appetite, fever, nausea, headache, fatigue and drowsiness. * Repeated contact can cause severe eye damage. * Repeated high exposure may affect the liver, kidneys and blood cells.

Are all antineoplastic drugs hazardous?

Antineoplastic drugs, also known as chemotherapy, cytotoxic and oncology drugs, are used to treat cancer, as well as arthritis, multiple sclerosis, and other non-cancer medical conditions. Most antineoplastic drugs are classified by NIOSH as hazardous drugs.

What is antineoplastic agent?

antineoplastic agent. antineoplastic therapy a regimen that includes chemotherapy, aimed at destruction of malignant cells using a variety of agents that directly affect cellular growth and development. Chemotherapy is but one of a variety of methods available in the treatment of cancer.

What are the adverse health effects of antineoplastic drugs?

Overview. The adverse health effects associated with antineoplastic agents (cancer chemotherapy drugs, cytotoxic drugs) in cancer patients and some non-cancer patients treated with these drugs are well documented. The very nature of antineoplastic agents make them harmful to healthy cells and tissues as well as the cancerous cells.

How do antineoplastics work?

Antineoplastics or anticancer drugs affect the process of cell division i.e. are antiproliferative. They damage the DNA and initiate apoptosis, preventing the development and spread of neoplastic cells.

Why should I be concerned about exposure to antineoplastic drugs?

Why should I be concerned about exposure? 1 We know that cancer patients who are taking antineoplastic drugs have an increased risk of infertility. 2 People who work with these drugs have also been found to have an increased risk… 3 Antineoplastic drugs work by targeting and killing rapidly dividing cancerous cells,…