What drug class is neumega?

Neumega belongs to a group of drugs called thrombopoietic growth factors, which help the body make more platelets. This medication comes in an injectable form and is given just under the skin once daily. Common side effects include slight water weight gain, shortness of breath, and low red blood cell count (anemia).

What class of drug is Oprelvekin?

Drug type: Oprelvekin is a biologic response modifier. It is classified as a cytokine.

What is the primary action of Oprelvekin neumega which is a drug in the interleukin IL classification?

The primary hematopoietic activity of Neumega is stimulation of megakaryocytopoiesis and thrombopoiesis. Neumega has shown potent thrombopoietic activity in animal models of compromised hematopoiesis, including moderately to severely myelosuppressed mice and nonhuman primates.

What side effect should be monitored related to platelets?

Common side effects of platelets include:

• Hemolytic transfusion reactions.
• Febrile non-hemolytic reactions.
• Allergic reactions ranging from hives to severe (anaphylaxis)
• Septic reactions.
• Transfusion Related Acute Lung Injury (TRALI)
• Circulatory overload.
• Transfusion associated graft versus host disease.

What is neumega used for?

Neumega (oprelvekin) is a protein that stimulates production of platelets in the blood used to prevent platelets from becoming dangerously low in certain people receiving chemotherapy that can result in bone marrow suppression or the need for blood platelet transfusions.

Is Oprelvekin used for thrombocytopenia?

Oprelvekin is indicated for the prevention of severe thrombocytopenia and the reduction of platelet transfusion requirements following myelosuppressive chemotherapy in patients with nonmyeloid malignancies at high risk of severe thrombocytopenia.

What is Oprelvekin used for?

Naturally occurring interleukin-11 is produced by bone marrow cells in the body and helps to make platelets, which are necessary for proper clotting of blood. Oprelvekin is used to help prevent low platelet counts caused by treatment with some cancer medicines.

What is the mechanism of action of Oprelvekin?

Mechanism of Action: Oprelvekin functions similarly to endogenous interleukin (IL)-11 and stimulates platelet production. The primary hematopoietic activity of oprelvekin is stimulation of megakaryocytopoiesis and thrombopoiesis.

What does desmopressin treat?

Desmopressin is used to treat central cranial diabetes insipidus. This is a condition that causes the body to lose too much fluid and become dehydrated. It is also used to control bedwetting (nocturnal enuresis), and the frequent urination and increased thirst caused by certain types of brain injury or brain surgery.

Can you eat after taking desmopressin?

Conclusions: The gastrointestinal absorption of desmopressin is reduced and delayed if administered with or 1.5 hours after a meal. This decreased absorption of desmopressin did not have an impact on the antidiuretic action of the drug since all treatment regimens elicted a maximal response.

Can I drink water after taking desmopressin?

Limit your intake of water and other fluids while you are using desmopressin. Drinking too much water may lead to a serious, life-threatening electrolyte imbalance. Fluid restriction is especially important in children and older adults using desmopressin.

What is Neumega?

Neumega is a sterile, white, preservative-free, lyophilized powder for subcutaneous injection upon reconstitution. Reconstitute the Neumega 5 mg vial using the 1.0 mL of Sterile Water for Injection, USP (without preservative) contained in the pre-filled syringe included in the kit.

Where do you inject Neumega?

Neumega can be injected into the skin of your upper legs (thighs), your abdomen (stomach), your hip, or your upper arms if not self-injecting. [picture] You should inject the Neumega into one of these different places of your body every time you use it.

How do I protect the Neumega powder?

The Neumega powder must be protected from light. Every time you give yourself a dose of Neumega, you must use a new bottle of Neumega powder and a new pre-filled syringe of Sterile Water for Injection, USP. There is an expiration date printed on the bottle of the Neumega powder and on the pre-filled syringe.

Does Neumega interact with other medications or foods?

Drug interactions between Neumega and other drugs have not been fully evaluated. Based on in vitro and nonclinical in vivo evaluations of Neumega, drug-drug interactions with known substrates of P450 enzymes would not be predicted. No studies have been performed to assess the carcinogenic potential of Neumega.