What does metastatic nodal disease mean?

Metastatic cancer is commonly called stage IV cancer or advanced cancer. It occurs when cancer cells break off from the original tumor, spread through the bloodstream or lymph vessels to another part of the body, and form new tumors. Nearby lymph nodes are the most common place for cancer to metastasize.

What is metastatic nodal involvement?

N1 is defined as “metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension”. Lymph node involvement is one of the most important prognosistic factors in non-small cell lung cancer patients.

What is a metastatic lymph node?

Secondary cancer in distant lymph nodes If cancer cells settle in the distant lymph nodes, it is known as secondary or metastatic cancer. When the cancer cells in the distant lymph nodes are examined under a microscope, they look like cells from the primary cancer.

Can metastasis be cured?

In some situations, metastatic cancer can be cured, but most commonly, treatment does not cure the cancer. But doctors can treat it to slow its growth and reduce symptoms. It is possible to live for many months or years with certain types of cancer, even after the development of metastatic disease.

What stage is lymph node metastasis?

Stage IV (metastatic): The tumor can be any size and has spread to other organs, such as the bones, lungs, brain, liver, distant lymph nodes, or chest wall (any T, any N, M1). Metastatic cancer found when the cancer is first diagnosed occurs about 6% of the time. This may be called de novo metastatic breast cancer.

Can lymph nodes be removed?

Lymph node removal is a surgical procedure to take out one or more of your lymph nodes. Your doctor may recommend you have this procedure if you’ve been diagnosed with cancer. There are two main reasons for removing lymph nodes. If you have cancer, one or more lymph nodes may be removed to check whether it has spread.

Is metastatic cancer curable?

What are intrathoracic hilar and mediastinal lymph node metastases?

Intrathoracic hilar and mediastinal lymph node metastases (HMLNMs) are a usual mode of spread of lung or esophagus carcinomas.

What is a metastatic nodal disease?

Metastases are frequently found in nodes that are not enlarged by conventional criteria[25]. The key to successful interpretation of imaging for nodal diseases requires a thorough understanding of the normal nodal anatomy, pathways of dissemination, clinical and pathological features of the disease. Patterns of tumour spread

What is the prognosis of Intrathoracic hilar carcinoma (hmlnms)?

Intrathoracic hilar or mediastinal lymph node metastases (HMLNMs) of extrathoracic carcinomas are infrequent. Their treatment strategy is not established and their prognosis poorly known.

What biologic indices are used in the evaluation of nodal metastases?

Other biologic indices can help to alert the radiologist to the likelihood of nodal metastases. For example, in patients with prostate cancer, a high prostate-specific antigen (PSA) level or high Gleeson score on biopsy have a higher likelihood of nodal involvement and extracapsular prostatic disease and nodal disease.