What do you mix tobramycin IV with?

When given by infusion, Tobramycin Injection may be diluted (with 0.9% Sodium Chloride Intravenous Infusion or 5% Dextrose Intravenous Infusion) to volumes of 50-100 ml for adult doses. For children, the volume of diluent should be proportionately less than for adults.

What is IV tobramycin used for?

Tobramycin is an aminoglycoside (ah-meen-oh-GLY-ko-side) antibiotic. Tobramycin fights infections that are caused by bacteria. Tobramycin injection is used to treat bacterial infections of the skin, heart, stomach, brain and spinal cord, lungs, and urinary tract (bladder and kidneys).

What is the dosing for tobramycin?

The FDA-approved dose is 6 to 7.5 mg/kg/day IV or IM divided every 6 to 8 hours. 2.5 mg/kg/dose IV or IM every 12 hours. The FDA-approved dose is 6 to 7.5 mg/kg/day IV or IM divided every 6 to 8 hours.

What are adverse effects to tobramycin?

Common side effects of Tobramycin for Injection include dizziness, spinning sensation (vertigo), ringing in the ears, kidney problems, anemia, fever, rash, itching, nausea, vomiting, stomach upset, loss of appetite, diarrhea, headache, lethargy, injection site reactions (pain, irritation, or redness), and confusion.

How do you administer tobramycin IV?

When tobramycin is injected intravenously, it is usually infused (injected slowly) over a period of 20 to 60 minutes once every 6 or 8 hours. The length of your treatment depends on the type of infection you have. You may receive tobramycin injection in a hospital or you may administer the medication at home.

What nebulizer is used for tobramycin?

Tobramycin is especially formulated to be used with a PARI LC PLUS™ nebulizer. Tobi® is used together with a DeVilbiss® Pulmo-Aide® compressor, while Bethkis® is used together with a PARI Vios air compressor. An air compressor is used with a nebulizer to turn the medicine into a fine spray.

What bacteria does tobramycin treat?

Tobramycin has a narrow spectrum of activity and is active against Gram-positive Staphylococcus aureus and various Gram-negative bacteria. Clinically, tobramycin is frequently used to eliminate Pseudomonas aeruginosa in cystic fibrosis patients.

What drugs interact with tobramycin?

Some products that may interact with this drug include: botulinum toxin, neostigmine, pyridostigmine. Other medications that may affect hearing or cause kidney damage may increase the risk of hearing loss or kidney problems if taken with tobramycin.

How do you give tobramycin IV?

Who should not use tobramycin?

Tobramycin ophthalmic is not approved for use by anyone younger than 2 months old.

What is another name for tobramycin?

Tobramycin is a prescription aminoglycoside antibiotic used as treatment against Gram-positive and Gram-negative bacteria. Tobramycin is available under the following different brand names: Nebcin injection.

What are the modes of action of tobramycin?

Inhibitors of cell wall synthesis.

How to dose tobramycin?

– Children under 5 years old: 2.5 mg/kg/dose intravenously/intramuscularly every 8 hours – Children 5 years and older: 2-2.5 mg/kg/dose intravenously/intramuscularly every 8 hours – Hemodialysis: 1.25-1.75 mg/kg/dose post dialysis

Is tobramycin a penicillin medication?

combined with an antibiotic that interferes with cell-wall synthesis affects some enterococcal strains synergistically. The combination of penicillin G and tobramycin results in a synergistic…

How is tobramycin administered?

Tobramycin Description.