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What are bZIP transcription factors?

What are bZIP transcription factors?

bZIP transcription factors are effectors downstream of mitogenic stimulation, stress responses (oxidative, ER, heat), and cytokine stimulation.

What is bZIP in biology?

The basic region leucine zipper (bZIP) proteins form one of the largest families of transcription factors in eukaryotic cells. These proteins dimerize through their leucine repeats to form a coiled coil with two flanking α-helices that constitute the basic region that contacts DNA bases.

What is bZIP?

bzip2 is a free and open-source file compression program that uses the Burrows–Wheeler algorithm. It only compresses single files and is not a file archiver. It was developed by Julian Seward, and maintained by Mark Wielaard and Micah Snyder.

What is GZIP compression?

GZIP, short for GNU Zip, is the most popular lossless data compression method on the web. It allows you to reduce the size of your site’s HTML pages, stylesheets, and scripts. Apart from being a data compression algorithm, GZIP is also a file extension (. gz) and a software used for file compression/decompression.

What is a transcription factor for dummies?

Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that initiate and regulate the transcription of genes.

What does a zinc finger do?

Abstract. Zinc finger proteins are among the most abundant proteins in eukaryotic genomes. Their functions are extraordinarily diverse and include DNA recognition, RNA packaging, transcriptional activation, regulation of apoptosis, protein folding and assembly, and lipid binding.

What is Bgzip?

DESCRIPTION. Bgzip compresses files in a similar manner to, and compatible with, gzip(1). The file is compressed into a series of small (less than 64K) ‘BGZF’ blocks. This allows indexes to be built against the compressed file and used to retrieve portions of the data without having to decompress the entire file.

What does E4BP4 stand for?

1 Department of Gene Expression and Development, The Roslin Institute (Edinburgh), Roslin, Midlothian. Scotland EH25 9PS. [email protected] E4BP4, a mammalian basic leucine zipper (bZIP) transcription factor, was first identified through its ability to bind and repress viral promoter sequences.

What is E4BP4 (NFIL3)?

Until recently, the basic leucine zipper transcription factor E4BP4 (also known as NFIL3) was of little interest to immunologists, being best known for its role in regulating circadian rhythm in chick pineal gland. However, characterisation of E4bp4(-/-) mice, independently generated in four differe …

Why can’t I open E4B files on my computer?

If you cannot open the E4B file on your computer – there may be several reasons. The first and most important reason (the most common) is the lack of a suitable software that supports E4B among those that are installed on your device. A very simple way to solve this problem is to find and download the appropriate application.