Advice

Is ribavirin still available?

On April 16, 2019, the FDA announced the discontinuation of Merck’s Rebetol (ribavirin) oral solution. — The discontinuation was due to business reasons and is not due to any safety, efficacy or quality issues. — Rebetol will be discontinued on or near June 2019. — Brand Rebetol capsules will continue to be available.

Is ribavirin still available?

On April 16, 2019, the FDA announced the discontinuation of Merck’s Rebetol (ribavirin) oral solution. — The discontinuation was due to business reasons and is not due to any safety, efficacy or quality issues. — Rebetol will be discontinued on or near June 2019. — Brand Rebetol capsules will continue to be available.

Why ribavirin is used with interferon?

Ribavirin inhibits viral growth, has anti-viral properties and interrupts the way the hepatitis C virus absorbs genetic material when it replicates. In the majority of cases, for the treatment of hepatitis C ribavirin is used alongside interferon. Ribavirin is ineffective against hepatitis C on its own.

Is ribavirin still used for HCV?

Ribavirin has been an integral component of hepatitis C therapy. The use of ribavirin with interferon or peginterferon for the treatment of hepatitis C is no longer recommended due to the poor efficacy and high rate of adverse effects with this regimen.

How much does ribavirin cost?

Wholesale Prices of Ribavirin

Drug Name Dose Price Per Month for Generic*
Ribavirin 800–1,400 mg daily 800 mg: $1,192 1,000 mg: $1,490 1,200 mg: $1,787 1,400 mg: $2,085

Which company makes ribavirin?

Ribavirin for intravenous administration is of limited availability, produced by ICN Pharmaceuticals/Valent Pharamceuticals International for compassionate use under an investigational new drug application.

What is sofosbuvir used for?

The US FDA has recently (6 December, 2013) approved sofosbuvir under the brand name Sovaldi for the treatment chronic HCV infection under a breakthrough therapy designation, because it has shown a substantial improvement over the other available therapies.

How effective is sofosbuvir against hepatitis C virus?

Sofosbuvir, a recently approved nucleotide analog, is a highly potent inhibitor of the NS5B polymerase in the Hepatitis C virus (HCV), and has shown high efficacy in combination with several other drugs, with and without PEG-INF, against HCV.

What is ribavirin used for?

Usage/Application: Ribavirin is used in combination with other antiviral medications Side Effect: Nausea, diarrhea, stomach upset, headache, dizziness, blurred vision, trouble sleeping, cough, low a read more… read more… Triveni Interchem Private Limited (Group Of Triveni… read more… Storage Instruction: Store in a cool, dry & dark place.

What is sofosbuvir (L-alanine)?

Sofosbuvir is a new drug candidate for hepatitis C treatment, with the chemical name L-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-uridylyl]-, 1-methylethyl ester and a molecular formula of C22H29FN3O9P.[8]