Does PASH increase risk of breast cancer?

PASH can sometimes be felt as a lump during a monthly self-breast exam, but is most often found during a routine mammogram. It can also be found during a biopsy for an unrelated breast condition. PASH is not cancer and it doesn’t increase your risk for developing breast cancer in the future.

Does stromal fibrosis turn into cancer?

Stromal fibrosis is a common finding on percutaneous breast biopsy, with an incidence ranging from 2.1% to 9.0% depending on the series. Stromal fibrosis has a wide spectrum of imaging appearances on mammogram, ultrasound and MRI….Table 3.

What is stromal fibrosis?

Stromal fibrosis is a histopathological finding categorized as fibrocystic change [1]. It is a dense collagenous breast mass with little glandular or vascular tissue [2]. Although the disease typically occurs in premenopausal women, cases have been reported in postmenopausal women as well [2-5].

What does PASH mean in a breast biopsy?

Abstract. Pseudoangiomatous stromal hyperplasia (PASH) is frequently a microscopic incidental finding in breast biopsies performed for benign or malignant disease. However, it may also produce a mass lesion. We reviewed PASH seen first as a tumor in 40 women aged 14 to 67 years (mean, 37 years).

Is PASH serious?

A pseudoangiomatous stromal hyperplasia (PASH) is a benign (harmless) lesion found in breast tissue. Mostly made from collagen, which is also known as stromal cells, a PASH can often be felt as a lump during a routine breast exam.

When should PASH be removed?

Five Things Physicians and Patients Should Question PASH is a benign breast condition that can present as either an abnormality on imaging or a palpable mass. Unless the lesion is suspicious or a patient has symptoms, a diagnosis of PASH on needle biopsy does not necessitate surgical removal.

Can PASH be misdiagnosed?

PASH is sometimes misdiagnosed as a fibroadenoma. The major cause behind PASH is still not known, however, the risk of this rare disease is higher in women suffering from a benign fibrocystic breast problem. Most of the time, this condition shows no symptoms.

Is stromal fibrosis painful?

With stromal fibrosis, the breasts may develop lumps or thickening of breast tissue. Quite often the condition is accompanied by tenderness and pain in the breast.

Should PASH be removed?

PASH is a benign breast condition that can present as either an abnormality on imaging or a palpable mass. Unless the lesion is suspicious or a patient has symptoms, a diagnosis of PASH on needle biopsy does not necessitate surgical removal.

How is PASH treated?

Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a benign mesenchymal lesion with incidental histologic findings. Surgical excision is recommended as the treatment of choice for PASH, although the recurrence rates after excision range from 15% to 22%.

Does PASH require surgery?

What is Pash (Pseudoangiomatous stromal hyperplasia)?

Pseudoangiomatous stromal hyperplasia (PASH) is a type of non-cancerous breast lesion. It typically affects women in the reproductive age group.

Is Pash a cancer?

Pseudoangiomatous stromal hyperplasia (PASH) is a type of non-cancerous breast lesion. It typically affects women in the reproductive age group. While PASH itself is benign, it may mimic cancer (specifically angiosarcoma).

What is Pash (peripheral arterial hormone imbalance)?

PASH is a benign (not cancer) breast condition. It’s more common in premenopausal women (women who haven’t been through the menopause), but can affect women of any age. PASH can also affect men, but this is rare. It’s not known what causes PASH, but it’s thought it might be linked to hormonal changes in the body.

What is the pathophysiology of Pash at biopsy?

PASH can be a relatively common incidental finding at breast biopsy. On histology, it is characterized by the presence of open slit-like spaces in dense collagenous stroma which is lined by a discontinuous layer of flat, spindle-shaped myofibroblasts with bland nuclei.